Amoebiasis continues to be a major cause of morbidity and mortality in children in developing countries. Entamoeba histolytica\r\ninfections are commonly observed in tropical and subtropical regions of the world including Iran. In developed countries\r\nEntamoeba histolytica infections are commonly seen in travelers, recent immigrants, homosexual men, and inmates of institutions.\r\nThe disease is more severe in the two extremes of life. This paper paper describes a four-month-old male infant with Entamoeba\r\nhistolytica presenting initially with refusal of feeds, hyperactive bowel sound, vomiting, and diarrhea. A fecal sample was positive for\r\nEntamoeba histolytica by Lugol�s iodine solution and the concentration technique. He was successfully treated with metronidazole\r\nfor 5 days. This case illustrates that Entamoeba species could be pathogenic in young infant; therefore, awareness of the infection,\r\naggressive approach to diagnosis, and early initiation of treatment continue to be critical component of infection control.
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